The Effect of Parenteral and Oral Immunization on Encephalomyocarditis Infection in Mice
| Autor: | T. G. Lawrence, H H Collins |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
viruses
Administration Oral Virulence General Biochemistry Genetics and Molecular Biology Virus Microbiology Feces Mice Formaldehyde Animals Encephalomyocarditis virus Viral shedding Antiserum biology Viral Vaccines biology.organism_classification Virology Myocarditis Oral immunization Rickettsia Immunization Encephalitis Female |
| Zdroj: | Experimental Biology and Medicine. 133:1066-1069 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-133-34626 |
| Popis: | SummaryActive immunization with parenteral formalin-inactivated EMC virus or with oral living-attenuated EMC virus protets mice against lethal oral challenge with virulent virus and prevents subsequent viral shedding in the feces. Similar results can be obtained by passively immunizing mice with rabbit anti-EMC antiserum. Coproantibody was recovered only from orally immunized mice, and was thus not correlated with resistance to fecal shedding of virus. |
| Databáze: | OpenAIRE |
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