Critical research gaps in electronic cigarette devices and nicotine aerosols
| Autor: | Zhengrong Cui, Salomon A Stavchansky, Jamie E. Spahn |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Aerosols
Nicotine Aerosolize business.industry medicine.medical_treatment Pharmaceutical Science 02 engineering and technology Electronic Nicotine Delivery Systems 021001 nanoscience & nanotechnology Critical research 030226 pharmacology & pharmacy law.invention Toxicology studies 03 medical and health sciences 0302 clinical medicine Risk analysis (engineering) law medicine Smoking cessation 0210 nano-technology business Electronic cigarette medicine.drug |
| Zdroj: | International journal of pharmaceutics. 593 |
| ISSN: | 1873-3476 |
| Popis: | Electronic cigarettes (e-cigs) are devices that aerosolize nicotine-containing liquids for delivery as an inhaled vapor. E-cigs are currently marketed as smoking cessation devices, though the emergence and rapid adoption of these devices in recent years has sparked a great deal of concern over their safety. Given the plethora of devices and nicotine solutions available on the market and the lack of regulation and quality control, it is imperative that these devices and nicotine formulations are studied to assess critical operating parameters, the pharmacokinetic profiles of the inhaled nicotine, and the toxicity profiles of the e-cig aerosols. This review aims to deliver an overview of current research regarding electronic cigarette devices, nicotine-containing liquid formulations, pharmacokinetics of nicotine, and toxicology studies in order to highlight areas lacking in research or requiring greater standardization and regulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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