Distress in patients with bleeding disorders: a single institutional cross-sectional study

Autor:	Anthony DeBalsi, Vaughn Barry, Christine L. Kempton, Sidney F. Stein, Maria Ribeiro, Mary Ellen Lynch, Shanna Mattis, Ana G. Antun, H. G. Cohen, D. Hicks, Duc Quang Tran, Kesley D Tyson, C. L. Truss
Rok vydání:	2015
Předmět:	Adult Male Pediatrics medicine.medical_specialty Cross-sectional study Hemorrhage Disease Logistic regression Haemophilia Cohort Studies Quality of life medicine Humans Genetics (clinical) Depression (differential diagnoses) business.industry Depression Medical record Hematology General Medicine medicine.disease Distress Cross-Sectional Studies Physical therapy Quality of Life Female business
Zdroj:	Haemophilia : the official journal of the World Federation of Hemophilia. 21(6)
ISSN:	1365-2516
Popis:	Introduction Distress may affect a patient's ability to cope with and manage disease. Aim To report distress prevalence in adult patients with bleeding disorders and determine whether specific clinical and health characteristics, including disease severity and employment status, are associated with distress. Methods Patients who visited a Haemophilia Treatment Centre (HTC) between January 1st, 2012 through February 28th, 2014 and who completed a distress screen, pain screen and questionnaire were evaluated cross sectionally. Distress was measured by the National Comprehensive Cancer Network Distress Management Tool, which allowed patients to rate recent distress on a 0–10 point scale. A rating of five or more was categorized as high distress. Pain was measured by the Brief Pain Inventory Short Form, which asked patients to rate pain types on 0–10 point scales. Patients reported employment and other demographic and behavioural information on the questionnaire. Primary diagnosis, age, HIV and HCV status were abstracted from medical records. Adjusted logistic regression was used to identify distress associations. Results High distress prevalence among 152 patients with bleeding disorders was 31.6%. Unemployment, disability, greater depressive symptoms and higher pain were associated with high distress in multivariable models. Bleeding disorder diagnosis, race/ethnicity, HIV/HCV status and on-demand treatment regimen were not associated with high distress. Conclusion Distress among patients with congenital bleeding disorders followed at a comprehensive HTC was high and similar to that reported among patients with cancer. Future research should determine whether distress impacts clinical outcomes in patients with bleeding disorders as demonstrated in other chronic disorders.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14bedb25f31fe88ad20a23ef067f563 https://pubmed.ncbi.nlm.nih.gov/26179213 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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