Studies on the hemodynamic changes in the perfused hindlimb induced by the electrostimulation of the sinus nerve in the dog
| Autor: | Franco Rengo, Mario Condorelli, G. Perez, Massimo Chiariello, Lorenzo De Caprio, Luigi Saccà, Bruno Trimarco |
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| Rok vydání: | 1976 |
| Předmět: |
Atropine
Guanethidine Male Haemodynamic response Hemodynamics Blood Pressure Pressoreceptors Vasodilation Hindlimb General Biochemistry Genetics and Molecular Biology Norepinephrine Dogs medicine Animals General Pharmacology Toxicology and Pharmaceutics Sinus (anatomy) business.industry General Medicine Acetylcholine Electric Stimulation Vasomotor System Carotid Sinus medicine.anatomical_structure Anesthesia Reflex Female business medicine.drug |
| Zdroj: | Life Sciences. 19:1387-1397 |
| ISSN: | 0024-3205 |
| DOI: | 10.1016/0024-3205(76)90439-2 |
| Popis: | The effects of intravenous administration of guanethidine and guanethidine plus atropine on the reflex vasodilatation induced in the perfused hindlimb by the electrostimulation of the sinus nerve were studied in dogs. Guanethidine induced a marked decrease in the reflex response of the perfused hindlimb. Moreover, the following administration of atropine completely abolished the hemodynamic response to the sinus nerve stimulation. These findings suggest that the cholinergic system is involved, along with the sympathetic and the histaminegic system, in the genesis of the reflex vasodilatation produced by the electrostimulation of the sinus nerve. |
| Databáze: | OpenAIRE |
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