THE PASSAGE OF FAT EMULSION ACROSS THE HUMAN PLACENTA
| Autor: | M. C. Elphick, David Hull, G. M. Filshie |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Fat Emulsions Intravenous medicine.medical_specialty Phospholipid Fatty Acids Nonesterified chemistry.chemical_compound Pregnancy Internal medicine medicine Humans Maternal-Fetal Exchange Triglycerides chemistry.chemical_classification Fetus Triglyceride business.industry Infant Newborn Obstetrics and Gynecology Fatty acid Fetal Blood medicine.disease Endocrinology chemistry Biochemistry Emulsion Arterial blood Female lipids (amino acids peptides and proteins) Composition (visual arts) business |
| Zdroj: | BJOG: An International Journal of Obstetrics and Gynaecology. 85:610-618 |
| ISSN: | 1471-0528 1470-0328 |
| DOI: | 10.1111/j.1471-0528.1978.tb14930.x |
| Popis: | Six patients near term were given an intravenous infusion of a fat emulsion (Intralipid) a few hours before normal delivery or Caesarean section. Six other non-infused patients were studied as controls. Maternal venous and umbilical venous and arterial blood samples were taken at delivery and analyzed for individual fatty acid concentrations in triglyceride, free fatty acid (FFA) and phospholipid fractions. The emulsion, being rich in oleic and linoleic acids, affected the composition of the maternal triglycerides. The fetal lipids were also altered and the infusions resulted in large positive umbilical venous-arterial (v-a) differences in FFA and triglyceride fatty acid concentrations, but this was not the case for phospholipid concentrations. The fatty acids with the largest v-a differences were those prominent in the emulsion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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