Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects

Autor: Thomas E. Nichols, Gwenaëlle Douaud, Timothy B. Brown, Kamil Ugurbil, Gregory C. Burgess, Susan Y. Bookheimer, Daniel S. Marcus, Leah H. Somerville, Bruce Fischl, Matteo Bastiani, Stephen M. Smith, Sridhar Kandala, Michael P. Harms, Roger P. Woods, Ross W. Mair, Cynthia Hodge, David C. Van Essen, Silvia Mangia, Emma C. Robinson, Andre van der Kouwe, Jesper L. R. Andersson, Xiufeng Li, Melissa Terpstra, Michael A. Chappell, Douglas N. Greve, Saad Jbabdi, Keith Jamison, Matthew F. Glasser, Randy L. Buckner, Timothy S. Coalson, Daniele Mascali, Mirella Dapretto, Beau M. Ances, Lilla Zöllei, M. Dylan Tisdall, Stamatios N. Sotiropoulos, Steen Moeller, Kathleen M. Thomas, M Deanna, Essa Yacoub, David H. Salat
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Gerontology
Male
Aging
Medical and Health Sciences
030218 nuclear medicine & medical imaging
Resting-state
Diffusion
Functional connectivity
0302 clinical medicine
80 and over
Task
Beacon - Precision Imaging
Young adult
Child
Aged
80 and over
Human Connectome Project
Lifespan
Brain
Human Connectome
Middle Aged
Magnetic Resonance Imaging
Perfusion
Neurology
Child
Preschool
Biomedical Imaging
Female
Psychology
Adult
Connectomics
Adolescent
Cognitive Neuroscience
connectomics
resting-state
functional connectivity
task
diffusion
perfusion
development
aging
lifespan
Longevity
Development
Basic Behavioral and Social Science
Article
03 medical and health sciences
Sir Peter Mansfield Imaging Centre (SPMIC)
Young Adult
Neuroimaging
Clinical Research
Behavioral and Social Science
Connectome
Humans
Set (psychology)
Preschool
Aged
Protocol (science)
Neurology & Neurosurgery
Resting state fMRI
Psychology and Cognitive Sciences
Neurosciences
030217 neurology & neurosurgery
Zdroj: Harms, M P, Somerville, L H, Ances, B M, Andersson, J, Barch, D M, Bastiani, M, Bookheimer, S Y, Brown, T B, Buckner, R L, Burgess, G C, Coalson, T S, Chappell, M A, Dapretto, M, Douaud, G, Fischl, B, Glasser, M F, Greve, D N, Hodge, C, Jamison, K W, Jbabdi, S, Kandala, S, Li, X, Mair, R W, Mangia, S, Marcus, D, Mascali, D, Moeller, S, Nichols, T E, Robinson, E C, Salat, D H, Smith, S M, Sotiropoulos, S N, Terpstra, M, Thomas, K M, Tisdall, M D, Ugurbil, K, van der Kouwe, A, Woods, R P, Zöllei, L, Van Essen, D C & Yacoub, E 2018, ' Extending the human connectome project across ages : Imaging protocols for the Lifespan development and aging projects ', NeuroImage . https://doi.org/10.1016/j.neuroimage.2018.09.060
ISSN: 1095-9572
Popis: The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in participants from 5 to 100+years of age. HCP-D is enrolling 1300+healthy children, adolescents, and young adults (ages 5-21), and HCP-A is enrolling 1200+healthy adults (ages 36-100+), with each study collecting longitudinal data in a subset of individuals at particular age ranges. The imaging protocols of the HCP-D and HCP-A studies are very similar, differing primarily in the selection of different task-fMRI paradigms. We strove to harmonize the imaging protocol to the greatest extent feasible with the completed HCP-YA (1200+participants, aged 22-35), but some imaging-related changes were motivated or necessitated by hardware changes, the need to reduce the total amount of scanning per participant, and/or the additional challenges of working with young and elderly populations. Here, we provide an overview of the common HCP-D/A imaging protocol including data and rationales for protocol decisions and changes relative to HCP-YA. The result will be a large, rich, multi-modal, and freely available set of consistently acquired data for use by the scientific community to investigate and define normative developmental and aging related changes in the healthy human brain.
Databáze: OpenAIRE
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