Extending the human connectome project across ages: imaging protocols for the lifespan development and aging projects
Autor: | Thomas E. Nichols, Gwenaëlle Douaud, Timothy B. Brown, Kamil Ugurbil, Gregory C. Burgess, Susan Y. Bookheimer, Daniel S. Marcus, Leah H. Somerville, Bruce Fischl, Matteo Bastiani, Stephen M. Smith, Sridhar Kandala, Michael P. Harms, Roger P. Woods, Ross W. Mair, Cynthia Hodge, David C. Van Essen, Silvia Mangia, Emma C. Robinson, Andre van der Kouwe, Jesper L. R. Andersson, Xiufeng Li, Melissa Terpstra, Michael A. Chappell, Douglas N. Greve, Saad Jbabdi, Keith Jamison, Matthew F. Glasser, Randy L. Buckner, Timothy S. Coalson, Daniele Mascali, Mirella Dapretto, Beau M. Ances, Lilla Zöllei, M. Dylan Tisdall, Stamatios N. Sotiropoulos, Steen Moeller, Kathleen M. Thomas, M Deanna, Essa Yacoub, David H. Salat |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Gerontology
Male Aging Medical and Health Sciences 030218 nuclear medicine & medical imaging Resting-state Diffusion Functional connectivity 0302 clinical medicine 80 and over Task Beacon - Precision Imaging Young adult Child Aged 80 and over Human Connectome Project Lifespan Brain Human Connectome Middle Aged Magnetic Resonance Imaging Perfusion Neurology Child Preschool Biomedical Imaging Female Psychology Adult Connectomics Adolescent Cognitive Neuroscience connectomics resting-state functional connectivity task diffusion perfusion development aging lifespan Longevity Development Basic Behavioral and Social Science Article 03 medical and health sciences Sir Peter Mansfield Imaging Centre (SPMIC) Young Adult Neuroimaging Clinical Research Behavioral and Social Science Connectome Humans Set (psychology) Preschool Aged Protocol (science) Neurology & Neurosurgery Resting state fMRI Psychology and Cognitive Sciences Neurosciences 030217 neurology & neurosurgery |
Zdroj: | Harms, M P, Somerville, L H, Ances, B M, Andersson, J, Barch, D M, Bastiani, M, Bookheimer, S Y, Brown, T B, Buckner, R L, Burgess, G C, Coalson, T S, Chappell, M A, Dapretto, M, Douaud, G, Fischl, B, Glasser, M F, Greve, D N, Hodge, C, Jamison, K W, Jbabdi, S, Kandala, S, Li, X, Mair, R W, Mangia, S, Marcus, D, Mascali, D, Moeller, S, Nichols, T E, Robinson, E C, Salat, D H, Smith, S M, Sotiropoulos, S N, Terpstra, M, Thomas, K M, Tisdall, M D, Ugurbil, K, van der Kouwe, A, Woods, R P, Zöllei, L, Van Essen, D C & Yacoub, E 2018, ' Extending the human connectome project across ages : Imaging protocols for the Lifespan development and aging projects ', NeuroImage . https://doi.org/10.1016/j.neuroimage.2018.09.060 |
ISSN: | 1095-9572 |
Popis: | The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are two large-scale brain imaging studies that will extend the recently completed HCP Young-Adult (HCP-YA) project to nearly the full lifespan, collecting structural, resting-state fMRI, task-fMRI, diffusion, and perfusion MRI in participants from 5 to 100+years of age. HCP-D is enrolling 1300+healthy children, adolescents, and young adults (ages 5-21), and HCP-A is enrolling 1200+healthy adults (ages 36-100+), with each study collecting longitudinal data in a subset of individuals at particular age ranges. The imaging protocols of the HCP-D and HCP-A studies are very similar, differing primarily in the selection of different task-fMRI paradigms. We strove to harmonize the imaging protocol to the greatest extent feasible with the completed HCP-YA (1200+participants, aged 22-35), but some imaging-related changes were motivated or necessitated by hardware changes, the need to reduce the total amount of scanning per participant, and/or the additional challenges of working with young and elderly populations. Here, we provide an overview of the common HCP-D/A imaging protocol including data and rationales for protocol decisions and changes relative to HCP-YA. The result will be a large, rich, multi-modal, and freely available set of consistently acquired data for use by the scientific community to investigate and define normative developmental and aging related changes in the healthy human brain. |
Databáze: | OpenAIRE |
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