Multiple osteolytic lesions of the jaws in a patient with neurofibromatosis type I
| Autor: | Konstantina Delli, Makris Nikos, K. Tosios |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Neurofibromatosis type I medicine.medical_specialty Osteolysis Panoramic radiograph business.industry medicine.medical_treatment 030105 genetics & heredity medicine.disease Radiation therapy 03 medical and health sciences 030104 developmental biology medicine.anatomical_structure Granuloma Medicine Surgery Hard palate Radiology Oral Surgery Neurofibromatosis business Neurofibromatoses |
| Zdroj: | Oral Surgery, 12(2), 126-132 Oral Surgery |
| ISSN: | 1752-2471 |
| Popis: | We describe the case of a patient diagnosed with neurofibromatosis type1 (NF1) where unusually extensive and multiple osteolytic lesions ofboth jaws consistent with central giant cell granulomas (CGCG) causedmassive bone destruction and left her almost “jawless.” The patient wasa 58-year-old woman who at the age of 15 years was diagnosed withNF1 and at the age of 53 years underwent radiation therapy for nasalobstruction due to CGCG. The most significant intraoral findings werebrown tumors on the maxillary gingiva; bilateral expansion of the hardpalate; and a yellow mass on the floor of the mouth. Head and neckexamination revealed mandibular asymmetry and features consistentwith NF1. Panoramic radiograph and cone beam computed tomographydisclosed multiple radiolucent masses. Although the occurrence ofmultiple CGCG of the jaws in patients with NF1 is rare, early diagnosis,regular follow-up and proper therapeutic intervention may limit theextent of bone destruction. |
| Databáze: | OpenAIRE |
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