Poor survival for veterans with pathologic stage I non–small-cell lung cancer
| Autor: | Carol Callaway-Lane, Eric S. Lambright, Rhonda Pinkerman, Stephen A. Deppen, Jonathan C. Nesbitt, Melinda C. Aldrich, Joe B. Putnam, Eric L. Grogan, Pierre P. Massion, Heidi Chen, Jamii Baraka St. Julien |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Oncology medicine.medical_specialty Lung Neoplasms Population Veterans Health non-small cell lung cancer (NSCLC) Article Postoperative Complications Carcinoma Non-Small-Cell Lung Internal medicine medicine Humans Pneumonectomy education Lung cancer Veterans Affairs Aged Neoplasm Staging Retrospective Studies Pathologic stage education.field_of_study business.industry Proportional hazards model Hazard ratio Health Status Disparities General Medicine Middle Aged medicine.disease Survival Analysis Tennessee Surgery Treatment Outcome Multivariate Analysis Etiology business |
| Zdroj: | The American Journal of Surgery. 204:637-642 |
| ISSN: | 0002-9610 |
| DOI: | 10.1016/j.amjsurg.2012.07.008 |
| Popis: | Background Pathologic stage (pStage) IA and IB non–small-cell lung cancer (NSCLC) has a median survival time of 119 and 81 months, respectively. We describe the outcomes of veterans with pStage I NSCLC. Methods A retrospective review of 78 patients with pStage I NSCLC who underwent cancer resection was performed at the Tennessee Valley Veterans Affairs Hospital between 2005 and 2010. All-cause 30-day, 90-day, and overall mortality were determined. Survival was assessed with the Kaplan–Meier and Cox proportional hazards methods. Results There were 55 (71%) pStage IA and 23 (29%) IB patients. Thirty- and 90-day mortality was 3.8% (3 of 78) and 6.4% (5 of 78), respectively. Median survival was 59 and 28 months for pStage 1A and 1B, respectively. Postoperative events were associated with impaired survival on multivariable analysis (hazard ratio, 1.26, P = .03). Conclusions Veterans with pStage I NSCLC at our institution have poorer survival than the general population. More research is needed to determine the etiology of this disparity. |
| Databáze: | OpenAIRE |
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