Beyond Self-Monitored Plasma Glucose and HbA1c: the Role of Non-Traditional Glycaemic Markers in Gestational Diabetes Mellitus
| Autor: | Neuza Mendes, Rogério T. Ribeiro, Fátima Serrano |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Glycation End Products
Advanced Adult Blood Glucose medicine.medical_specialty Glycated Hemoglobin A endocrine system diseases 030209 endocrinology & metabolism Deoxyglucose 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pregnancy Internal medicine Blood Glucose Self-Monitoring medicine Humans Glycated Serum Albumin 030212 general & internal medicine Serum Albumin Glycated Hemoglobin Plasma glucose Haemoglobin A1c business.industry MAC MED MAF Obstetrics and Gynecology nutritional and metabolic diseases medicine.disease Gestational diabetes Diabetes Gestational Fructosamine chemistry Metabolic control analysis 1 5-Anhydroglucitol Female business Biomarkers Maternal Serum Screening Tests |
| Zdroj: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação instacron:RCAAP |
| Popis: | Strict glycaemic management is the cornerstone of metabolic control in gestational diabetes mellitus (GDM). Current monitoring standards involve self-monitoring plasma glucose (SMBG) and haemoglobin A1c (HbA1c). However, both have important limitations. SMBG only reflects instantaneous blood glucose and the inconvenience of self-collecting blood frequently results in poor compliance. HbA1c provides information on blood glucose levels from the previous 2 to 3 months and it is influenced by iron-deficient states, common during pregnancy. There is an urgent need for new shorter-term glycaemic markers, as glycated albumin, fructosamine or 1,5-anhydroglucitol. Glycated albumin seems especially interesting as it provides information on blood glucose levels over the foregoing 2-3 weeks and it is not influenced by iron deficiency or the dilutional anaemia of pregnancy. Fructosamine has a precise and inexpensive measurement and it is not affected by haemoglobin characteristics. This review further discusses the potential value of these non-traditional indicators of glycaemic control in patients with GDM, outlining their possible future applications. info:eu-repo/semantics/publishedVersion |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|