Myocardial Mechanics Parameters That Predict Left Ventricular Outflow Tract Obstruction in Patients With Hypertrophic Cardiomyopathy: A Cardiovascular Magnetic Resonance Feature Tracking Analysis
| Autor: | Jian Zhuang, Jinglei Li, Haiyun Yuan, Lei Huang, Jijin Lin, Lifeng Que, Hui Liu, Qianjun Jia, Yue Xi, Yuhao Dong |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Adolescent Heart Ventricles medicine.medical_treatment Cardiomyopathy Magnetic Resonance Imaging Cine Ventricular outflow tract obstruction Ventricular Outflow Obstruction 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Cardiac catheterization medicine.diagnostic_test Receiver operating characteristic business.industry fungi Hypertrophic cardiomyopathy Magnetic resonance imaging Odds ratio Cardiomyopathy Hypertrophic Middle Aged medicine.disease Confidence interval ROC Curve Case-Control Studies Cardiology Radiographic Image Interpretation Computer-Assisted Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Computer Assisted Tomography. 45:65-72 |
| ISSN: | 1532-3145 0363-8715 |
| DOI: | 10.1097/rct.0000000000000977 |
| Popis: | OBJECTIVE To identify left ventricular (LV) myocardial mechanics predictors of LV outflow tract obstruction (LVOTO) in patients with hypertrophic cardiomyopathy (HCM). METHODS Thirty-nine adults with HCM and 21 controls underwent cardiovascular magnetic resonance. The feature tracking (FT) analysis results of HCM patients with and without LVOTO and controls were compared. RESULTS Global radial strain measured on the short-axis slice (GRS-SAX) (odds ratio [OR], 1.09; 95% confidence interval [CI], 1.02-1.15; P < 0.01), global longitudinal strain measured on the long-axis slice (GLS-LAX) (OR, 1.81; 95% CI, 1.21-2.73; P < 0.01) and GRS measured on the long-axis slice (GRS-LAX) (OR, 1.07; 95% CI, 1.01-1.13; P = 0.02) were independent predictors of LVOTO. The combination of GRS-SAX plus GLS-LAX and GRS-LAX showed great discriminatory power for identifying LVOTO with an area under the receiver operating characteristic curve value of 0.91 (95% CI: 0.81-1.00). CONCLUSIONS In adult HCM patients, GRS-SAX, GLS-LAX, and GRS-LAX were independent predictors of LVOTO. The combination of GRS-SAX plus GLS-LAX and GRS-LAX showed great discriminatory power for identifying LVOTO. |
| Databáze: | OpenAIRE |
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