Synthesis of Molecularly Imprinted Polymers for the Selective Extraction of Polymyxins from Environmental Water Samples
| Autor: | Xuqin Song, Esther Turiel, Antonio Martín-Esteban, Limin He |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
environmental water
Polymers and Plastics medicine.drug_class Polymyxin polymyxins 01 natural sciences Article lcsh:QD241-441 03 medical and health sciences lcsh:Organic chemistry medicine polycyclic compounds molecularly imprinted solid-phase extraction GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) Detection limit 0303 health sciences Chromatography 030306 microbiology Chemistry 010401 analytical chemistry Extraction (chemistry) Molecularly imprinted polymer General Chemistry biochemical phenomena metabolism and nutrition equipment and supplies 0104 chemical sciences n/a Wastewater high-performance liquid chromatography-ultraviolet detector Precipitation polymerization Colistin bacteria lipids (amino acids peptides and proteins) Erratum Surface water medicine.drug |
| Zdroj: | Polymers Volume 12 Issue 1 Polymers, Vol 12, Iss 3, p 594 (2020) Polymers, Vol 12, Iss 1, p 131 (2020) |
| ISSN: | 2073-4360 |
| DOI: | 10.3390/polym12010131 |
| Popis: | The emergence of colistin resistance gen has aroused public concern. It is significant to assess the concentrations of polymyxins residues in aquatic environment since resistant bacteria carrying colistin resistance gen are frequently isolated from wastewater surface water and ground water. However no literature on the determination of polymyxins in water is available probably due to the absence of an efficient extraction method. Accordingly molecularly imprinted polymers were synthesized by precipitation polymerization with colistin as the template. The polymers were successfully used as sorbents for the determination of polymyxins from water based on molecularly imprinted solid-phase extraction and high-performance liquid chromatography&ndash ultraviolet detection. The molecularly imprinted cartridge showed excellent affinity and cross-reactivity to analytes in aqueous media. Recoveries obtained from water samples were between 65.9% and 90.1%, with relative standard deviations lower than 10.2%. Limits of detection were between 1.0 and 2.0 &mu g L&minus 1 concentration levels. Compared with C18 cartridge the molecularly imprinted cartridge could remove more interference from co-extracted matrices. This method is practical for the routine monitoring of polymyxin residues in environmental water which will benefit studies on drug-resistance and occurrence of polymyxins in the environment. |
| Databáze: | OpenAIRE |
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