Plasmid typing of Shigella sonnei epidemic strains and molecular relationship of their R-plasmids

Autor: C. Hardisson, F. J. Mendez, M. C. Mendoza, Ana J. González
Rok vydání: 1988
Předmět:
Zdroj: European Journal of Epidemiology. 4:158-163
ISSN: 1573-7284
DOI: 10.1007/bf00144744
Popis: We conducted a surveillance program on epidemic and/or endemic Shigella strains in Asturias (Spain), their frequency and dispersion in our community, and their R-plasmids. We analyzed initial isolates of Shigella sonnei from two epidemic outbreaks using antibiotic resistance patterns and plasmid profile analysis as epidemiological markers. We found that the 2 outbreaks were caused by different S. sonnei strains, which respectively carried one and two R-plasmids together with other plasmids. The molecular relationship among these and three other R-plasmids from two S. sonnei strains isolated during a previous outbreak, were studied by restriction enzyme analysis and DNA-DNA hybridizations. We were able to establish different levels of relationship among the six R-plasmids.
Databáze: OpenAIRE