Pd-Fe3O4/RGO: a Highly Active and Magnetically Recyclable Catalyst for Suzuki Cross Coupling Reaction using a Microfluidic Flow Reactor
| Autor: | B. Frank Gupton, Ali R. Siamaki, Hany A. Elazab, M. Samy El-Shall |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Materials science
suzuki cross-coupling Oxide Nanoparticle 02 engineering and technology 01 natural sciences Catalysis Coupling reaction law.invention chemistry.chemical_compound Chemical engineering law pd- fe3o4/rgo 010405 organic chemistry Graphene Process Chemistry and Technology Flow chemistry 021001 nanoscience & nanotechnology 0104 chemical sciences Volumetric flow rate 4-bromobenzaldehyde flow reactor chemistry TP155-156 0210 nano-technology Dispersion (chemistry) |
| Zdroj: | Bulletin of Chemical Reaction Engineering & Catalysis, Vol 14, Iss 3, Pp 478-489 (2019) |
| ISSN: | 1978-2993 |
| DOI: | 10.9767/bcrec.14.3.3518.478-489 |
| Popis: | There are several crucial issues that need to be addressed in the field of applied catalysis. These issues are not only related to harmful environmental impact but also include process safety concerns, mass and heat transfer limitations, selectivity, high pressure, optimizing reaction conditions, scale-up issues, reproducibility, process reliability, and catalyst deactivation and recovery. Many of these issues could be solved by adopting the concept of micro-reaction technology and flow chemistry in the applied catalysis field. A microwave assisted reduction technique has been used to prepare well dispersed, highly active Pd/Fe3O4 nanoparticles supported on reduced graphene oxide nanosheets (Pd-Fe3O4/RGO), which act as a unique catalyst for Suzuki cross coupling reactions due to the uniform dispersion of palladium nanoparticles throughout the surface of the magnetite - RGO support. The Pd-Fe3O4/RGO nanoparticles have been shown to exhibit extremely high catalytic activity for Suzuki cross coupling reactions under both batch and continuous reaction conditions. This paper reported a reliable method for Suzuki cross-coupling reaction of 4-bromobenzaldehyde using magnetically recyclable Pd/Fe3O4 nanoparticles supported on RGO nanosheets in a microfluidic-based high throughput flow reactor. Organic synthesis can be performed under high pressure and temperature by using a stainless steel micro tubular flow reactor under continuous flow reaction conditions. Optimizing the reaction conditions was performed via changing several parameters including temperature, pressure, and flow rate. Generally, a scalable flow technique by optimizing the reaction parameters under high-temperature and continuous reaction conditions could be successfully developed. |
| Databáze: | OpenAIRE |
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