Activated protein C resistance in a neonate with venous thrombosis
| Autor: | Charles Potter, Paul A. Foster, Nancy E. Kirschbaum, Eric Kodish |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Genotype Antithrombin III Polymerase Chain Reaction Inferior vena cava Gastroenterology Internal medicine medicine Humans Prothrombin time biology medicine.diagnostic_test business.industry Gene Amplification Infant Newborn Factor V Thrombophlebitis medicine.disease Thrombosis Pedigree Venous thrombosis Endocrinology Term Infant medicine.vein Mutagenesis Pediatrics Perinatology and Child Health Prothrombin Time biology.protein Partial Thromboplastin Time Activated protein C resistance business Protein C medicine.drug |
| Zdroj: | The Journal of Pediatrics. 127:645-648 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(95)70131-1 |
| Popis: | A term infant had a life-threatening inferior venal caval thrombosis during the first 24 hours of life. The plasma from the infant and his mother was found to be resistant to activated protein C and to be heterozygous for the factor V mutation (FV Leiden) associated with this disorder. The presence of this hereditary disorder should be considered in infants with thrombosis and in infants with conditions predisposing them to thrombosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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