Multiple chemiluminescence immunoassay detection of the concentration ratio of glycosylated hemoglobin A1c to total hemoglobin in whole blood samples

Autor: Huan Zhao, Xinghan Qiu, Enben Su, Li Huang, Yunfeng Zai, Yuan Liu, Hui Chen, Zunliang Wang, Zhu Chen, Song Li, Lian Jin, Yan Deng, Nongyue He
Rok vydání: 2021
Předmět:
Zdroj: Analytica chimica acta. 1192
ISSN: 1873-4324
Popis: The concentration ratio of glycosylated hemoglobin A1c (HbA1c) to total hemoglobin (Hb) has long been used to accurately determine stagewise diabetes because this parameter represents a reliable and accurate biomarker of mean 90-day blood glucose values. In this paper, we report a time-resolved chemiluminescence assay that can detect both Hb and HbA1c. For the determination of Hb, the interaction of heme in Hb with H
Databáze: OpenAIRE