Design improvements of the HIA-VAD based on animal experiments
| Autor: | Günter Rau, Gerhard Rakhorst, P. Harbott, Rolf Eilers, Helmut Reul |
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| Rok vydání: | 1994 |
| Předmět: |
Engineering
In vitro test Surface Properties medicine.medical_treatment Biomedical Engineering Medicine (miscellaneous) Bioengineering Blood Pressure Materials testing Biomaterials Electric Power Supplies Materials Testing medicine Animals Computer Simulation Heart valve Design improvement Pump design Flow resistance business.industry Thrombosis General Medicine Equipment Design Cardiac support medicine.anatomical_structure Ventricular assist device Hemorheology Computer-Aided Design Cattle Heart-Assist Devices Stress Mechanical business Blood Flow Velocity Biomedical engineering |
| Zdroj: | Artificial organs. 18(7) |
| ISSN: | 0160-564X |
| Popis: | Since 1990, development of the Helmholtz-Institute at Aachen ventricular assist device (HIA-VAD) was mainly based on animal tests performed at the University of Groningen. Although various in vitro tests had been performed previously, animal testing resulted in significant improvements of the HIA-VAD with regard to hemodynamics and pump handling. The most important design improvement was a new trileaflet polyurethane valve, which was designed as a blood-pump valve with an emphasis on opening behavior and flow resistance. Excellent hydrodynamic performance and sufficient durability of this new valve were confirmed by various in vitro tests. Further design and manufacturing improvements resulted in a completely transparent pump, which can be easily deaired and optically controlled. Final pump design was evaluated during subsequent animal tests, and the results are very promising in view of an efficient cardiac support system. |
| Databáze: | OpenAIRE |
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