Is the extent of left atrial fibrosis associated with body mass index in patients undergoing pulmonary vein isolation for atrial fibrillation?
| Autor: | Tomislav Sipic, Igor Sesto, Luka Rotkvić, Robert Bernat, Janko Szavits Nossan, Marinko Žulj, Ivan Gudelj, Krešimir Štambuk, Jure Mirat |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
business.industry Confounding Atrial fibrillation medicine.disease Fibrosis Body Mass Index Pulmonary vein Treatment Outcome Pulmonary Veins Recurrence Left atrial Interquartile range Internal medicine Atrial Fibrillation Catheter Ablation Cardiology medicine Humans In patient Body mass index Pulmonary vein isolation Cardiology and Cardiovascular Medicine business |
| Zdroj: | Kardiologia Polska. |
| ISSN: | 1897-4279 0022-9032 |
| Popis: | Background: Left atrial (LA) fibrosis is associated with a higher rate of recurrence of atrial fibrillation (AF) after pulmonary vein isolation (PVI). Body mass index (BMI) is strongly associated with the prevalence of AF, but there is insufficient data about the association between BMI and LA fibrosis. Aims: The aim of the study was to examine the association between LA fibrosis and BMI in patients with AF undergoing PVI. Methods: In 114 patients an electro-anatomical voltage map was created using the CARTO 3 three-dimensional system before PVI. The total fibrosis area (voltage criteria ≤0.5 mV), percentage, and the number of fibrotic areas were calculated. A general linear model was used to determine the differences in BMI with confounders between groups of patients with differing extents of fibrosis and numbers of focuses. Results: Advanced fibrosis was found in 53 (47%) patients, in up to 9 areas with a median of 2 and an interquartile range (IQR) of 0–3. The median total fibrotic area was 27.3 cm2 with an IQR of 0.1–30.3 cm2. Patients were stratified by percentage of fibrotic area |
| Databáze: | OpenAIRE |
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