Optical coherence tomography angiography to assess vascular remodeling of the choriocapillaris after low-fluence photodynamic therapy for chronic central serous chorioretinopathy
| Autor: | Pia Clara Pafundi, Giuseppe Caputo, Gilda Cennamo, Michela Cennamo, Giuseppe de Crecchio, Giovanni Cennamo, Federica Mirra |
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| Přispěvatelé: | Cennamo, Gilda., Cennamo, M., Caputo, G., Mirra, F., Pafundi, P. C., de Crecchio, G., Cennamo, Giovanni. |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Chorioretinopathy medicine.medical_treatment Biophysics Visual Acuity Photodynamic therapy Foveal thickness Dermatology Vascular Remodeling Chronic central serous chorioretinopathy Ophthalmology medicine Humans Pharmacology (medical) CSCR Fluorescein Angiography Aged Photosensitizing Agents Low fluence medicine.diagnostic_test business.industry Choroid Verteporfin Optical coherence tomography angiography Middle Aged Fluorescein angiography eye diseases Oncology Central Serous Chorioretinopathy Photochemotherapy Female sense organs business OCTA After treatment Tomography Optical Coherence medicine.drug |
| Zdroj: | Photodiagnosis and photodynamic therapy. 27 |
| ISSN: | 1873-1597 |
| Popis: | Background To evaluate the efficacy of optical coherence tomography angiography (OCTA) in identifying changes in the choriocapillaris layer after low-fluence verteporfin photodynamic therapy (vPDT) in patients affected by chronic central serous chorioretinopathy (CSCR). Methods Low-fluence vPDT was performed on 28 eyes of 27 patients with CSCR. All patients underwent the following tests at baseline and 6 months after treatment: best corrected visual acuity (BCVA), fluorescein angiography, indocyanine green angiography, enhanced depth imaging OCT and OCTA. Results Subretinal fluid was completely absorbed in 18 of the 28 affected eyes (64.3%) after low-fluence vPDT (“responders”), and incompletely absorbed in 10 eyes (35.7%) (“non responders”). BCVA was significantly improved (p = 0.006) whereas central foveal thickness and choroidal foveal thickness were significantly decreased (p = 0.001 and p = 0.00 respectively) 6 months after treatment in responders. Conclusions OCTA revealed a different pattern of vascular remodeling of the choriocapillaris between CSC patients who responded and those who did not respond to low-fluence vPDT. |
| Databáze: | OpenAIRE |
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