Effect of carotid endarterectomy on cerebral blood flow and its response to hypercapnia
| Autor: | T. Hunt, kevin Burnand, Lorraine Butler, N L Browse, C. C. R. Bishop |
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| Rok vydání: | 1987 |
| Předmět: |
Male
medicine.medical_treatment Hemodynamics Carotid endarterectomy Endarterectomy medicine.artery Medicine Humans Postoperative Period Aged business.industry Blood flow Carbon Dioxide Middle Aged medicine.disease Stenosis Carotid Arteries Cerebral blood flow Anesthesia Cerebrovascular Circulation cardiovascular system Surgery Female Internal carotid artery medicine.symptom business Hypercapnia circulatory and respiratory physiology Follow-Up Studies |
| Zdroj: | The British journal of surgery. 74(11) |
| ISSN: | 0007-1323 |
| Popis: | Cerebral blood flow (CBF) was measured in 14 patients before carotid endarterectomy, 3 h after surgery and 2 days postoperatively using the intravenous xenon-133 technique. In 11 of the patients CBF was remeasured at 6 months and in 8 patients CBF and the response to hypercapnia (5 per cent CO2 in air) was measured pre-operatively and 6 months following surgery. All operations were performed using an intraluminal Javid shunt and internal carotid artery (ICA) ‘stump’ pressure was recorded. CBF measured at 3 h after endarterectomy revealed a postoperative cerebral hyperperfusion with significantly increased flows in both hemispheres. There was a significant correlation between carotid cross clamping time and ipsilateral hemispheric CBF increase which implied an ischaemic aetiology for the hyperperfusion and supported the routine use of an intraluminal shunt in carotid endarterectomy. Six months after surgery, CBF had returned to its pre-operative value but reactivity to CO2 was significantly improved, which suggested that the operation had increased cerebral reserve. |
| Databáze: | OpenAIRE |
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