Copper-catalyzed C–H ethoxycarbonyldifluoromethylation of imidazoheterocycles

Autor:	Alakananda Hajra, Subhajit Mishra, Pallab Mondal, Monoranjan Ghosh, Susmita Mondal
Rok vydání:	2016
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Regioselectivity 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Ambient air chemistry.chemical_compound Copper catalyzed Organic chemistry Surface modification Physical and Theoretical Chemistry Thiazole
Zdroj:	Organic & Biomolecular Chemistry. 14:1432-1436
ISSN:	1477-0539 1477-0520
DOI:	10.1039/c5ob02363g
Popis:	A regioselective copper-catalyzed ethoxycarbonyl-difluoromethylation of imidazo[1,2-a]pyridines has been developed through sp(2) C-H bond functionalization with BrCF2CO2Et under ambient air. A series of ethoxycarbonyldifluoromethylated imidazo[1,2-a]pyridines with broad functionalities have been synthesized. This methodology is also applicable to imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ec900beacb1965c60acd4bade6452f https://doi.org/10.1039/c5ob02363g Zobrazit plný text záznamu