Mitosis and apoptosis in canine cutaneous histiocytoma and transmissible venereal tumour
| Autor: | Tolga Guvenc, R Haziroglu, Mehmet Orman, Mehmet Haligur |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Pathology
medicine.medical_specialty Skin Neoplasms TUNEL assay Histiocytoma Benign Fibrous General Veterinary biology Cell growth Mitosis Apoptosis Canine cutaneous histiocytoma Diagnosis Differential Dogs Ki-67 Antigen Ki-67 In Situ Nick-End Labeling biology.protein medicine Animals Immunohistochemistry Dog Diseases Differential diagnosis Venereal Tumors Veterinary |
| Zdroj: | Acta Veterinaria Hungarica. 50:315-321 |
| ISSN: | 1588-2705 0236-6290 |
| DOI: | 10.1556/avet.50.2002.3.8 |
| Popis: | Cell proliferation and apoptosis in canine cutaneous histiocytomas and transmissible venereal tumours were examined in twenty cases. The Ki-67 immunohistochemistry and Tunel methods were used to detect mitotic activity and apoptosis, respectively. The number of Ki-67 immunoreactive cells was 11.65 (+/- 1.1706) in canine cutaneous histiocytomas and 17 (+/- 2.1751) in transmissible venereal tumours. The mean values of apoptotic cells for canine cutaneous histiocytomas and transmissible venereal tumours were 13.25 (+/- 1.8758) and 8.52 (+/- 1.1007), respectively. It was considered that mitotic activity and apoptotic indices were useful in differentiation of canine cutaneous histiocytomas and transmissible venereal tumours. The correlation values for canine cutaneous histiocytomas and transmissible venereal tumours were 0.359 (+/- 0.330) and -0.232 (+/- 0.344), respectively. No significant (P0.05) correlation was found between mitosis and apoptosis in these two tumour types. |
| Databáze: | OpenAIRE |
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