Pathologic yawning in neuromyelitis optica spectrum disorders

Autor:	Natália Talim, Gilberto Belisário Campos, Lívia Edwiges Talim, Dagoberto Callegaro, Samira Luisa dos Apostolos Pereira, Marco Aurélio Lana-Peixoto
Rok vydání:	2014
Předmět:	Pediatrics medicine.medical_specialty Nausea business.industry Multiple sclerosis General Medicine Disease medicine.disease Sleep deprivation Neurology Neuromyelitis Optica Spectrum Disorders Anesthesia medicine Vomiting Neurology (clinical) Brainstem medicine.symptom business Hiccups
Zdroj:	Multiple sclerosis and related disorders. 3(4)
ISSN:	2211-0356
Popis:	Introduction Brainstem, hypothalamic and cerebral symptoms may occur in neuromyelitis optica spectrum disorders (NMOSD). However, pathologic yawning has not been previously described in NMOSD patients. Patients and methods Nine AQP4-IgG seropositive NMOSD patients experienced excessive yawning not related to sleep deprivation or fatigue. Results Patients were female, aged 19–57 years (median, 39 years) at disease onset. Excessive yawning spells were the presenting symptom of the disease in five patients, lasted 2–16 weeks, and usually occurred in association with nausea, vomiting and hiccups. Brain MRI was abnormal in all patients and most frequently showed brainstem and hypothalamic lesions. Conclusion Pathologic yawning may be a neglected although not a rare symptom in NMOSD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e14a6729874a37c3951a2fc934eb6c https://pubmed.ncbi.nlm.nih.gov/25877066 Zobrazit plný text záznamu Full Text from ScienceDirect