Short-channel functional near-infrared spectroscopy regressions improve when source-detector separation is reduced
| Autor: | Chantel R. Gaudet, James R. Goodwin, Andrew J. Berger |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Optical fiber
Materials science Radiological and Ultrasound Technology Speech recognition Flicker Near-infrared spectroscopy Detector Neuroscience (miscellaneous) Research Papers law.invention law Checkerboard Functional near-infrared spectroscopy Radiology Nuclear Medicine and imaging Detection theory Spectroscopy Biomedical engineering |
| Zdroj: | Neurophotonics. 1:015002 |
| ISSN: | 2329-423X |
| DOI: | 10.1117/1.nph.1.1.015002 |
| Popis: | In functional near-infrared spectroscopy (fNIRS) of human cerebral hemodynamics, dedicated surface-sensitive recording channels are useful for regressing out background hemodynamics and isolating activation-specific responses. A wide variety of source-detector separations have been utilized for this purpose. Here, we report a direct comparison of regression performance between two extremes of the reported range, 13 and 6 mm. Measurements of visual stimulation response (flickering radial checkerboard) were obtained from nine adults using a standard commercial source-detector grid with 13-mm diagonals, into which three extra detector fibers were placed to provide 6-mm channels at certain locations. When the NIRS recordings (17 total trials) were processed, the contrast-to-noise ratio was significantly higher with 6-mm regression channels than with 13 mm. The advantage could be due in part to the undesired sensing of brain activity by the 13-mm channels. We suggest that shorter distances be considered for optimal removal of superficial hemodynamics in NIRS signals from the adult brain. |
| Databáze: | OpenAIRE |
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