Septic complications and hospital admissions after transrectal ultrasound-guided prostate biopsy: incidence rates and outcomes in 913 consecutive biopsies

Autor: Vladimir Trkulja, Branimir Lodeta
Rok vydání: 2014
Předmět:
Zdroj: International urology and nephrology. 46(12)
ISSN: 1573-2584
Popis: Prostate cancer is the third most common cause of cancer death in Europe [1]. Transrectal ultrasound-guided prostate biopsy (TRUSB) is a cornerstone procedure for its diagnosis. When adequately indicated and performed, TRUSB is reliable, not too inconvenient for the patients and welltolerated [2]. The most common complications are hematuria, hematochezia, hemoejaculate and infections. To prevent infectious complications of TRUSB, routine prophylaxis is recommended by the leading urological associations [3, 4]. Fluoroquinolone antibiotics are commonly used in this setting due to their antimicrobial spectrum and high concentrations attained in the prostatic tissue [5]. Here, we report on incidence of prostate biopsy-related septic complications in a prospective series of consecutive patients submitted to TRUSB at General Hospital Varaždin, Croatia, between January 1, 2009 and December 31, 2013. All biopsies were performed by two experienced urologists and a standard routine prophylaxis was implemented in all patients: ciprofloxacin 2 9 500 mg/day starting a day before procedure and extending over four subsequent days. Regular check-ups were scheduled at 7 and 30 days post-procedure. Septic complication was defined as a presence of systemic inflammatory response syndrome with documented or presumed infection occurring within 30 days since TRUSB. A total of 913 procedures were performed in 913 patients. Until March 2
Databáze: OpenAIRE