Breast cancer molecular subtypes and receptor status among women at Potchefstroom Hospital: a cross-sectional study
| Autor: | Prince Kasongo Mwila, Jesslee M. du Plessis, Johanita Burger, Baudouin Kongolo Kakudji, Kanishka Naidu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Receptor Status Cross-sectional study Receptor ErbB-2 030231 tropical medicine Estrogen receptor Breast Neoplasms Gastroenterology 03 medical and health sciences South Africa 0302 clinical medicine Breast cancer Internal medicine Progesterone receptor Biomarkers Tumor Medicine cross-sectional study Humans Neoplasm Invasiveness 030212 general & internal medicine skin and connective tissue diseases Lymph node Aged Neoplasm Staging Retrospective Studies molecular subtypes business.industry Research receptor status General Medicine Middle Aged medicine.disease Potchefstroom medicine.anatomical_structure Cross-Sectional Studies Ki-67 Antigen Receptors Estrogen Population study Immunohistochemistry Female Menopause business Receptors Progesterone |
| Zdroj: | Pan African Medical Journal; Vol. 38 No. 1 (2021) The Pan African Medical Journal |
| ISSN: | 1937-8688 |
| Popis: | Introduction:this study aimed to determine the prevalence of receptor status and molecular subtypes in women with breast cancer treated at Potchefstroom Regional Hospital, South Africa and to analyze the association of molecular subtypes with some clinicopathologic characteristics of the tumor. Methods:the study population for this cross-sectional study consisted of 116 women with primary invasive breast cancer, treated at the hospital from 1stJanuary 2012 to 31stDecember 2018. Molecular subtypes were classified by immunohistochemical surrogates as luminal A (estrogen receptor (ER) positive and/or progesterone receptor (PR) positive, HER2-; Ki-67 |
| Databáze: | OpenAIRE |
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