Autor: |
Anna Bäcksbro-Saeidi, Sandra Gordon, Peter Agback, Bo Carlsson, Konrad F. Koehler, Peter Brandt, Stefan Rehnmark, Theresa Apelqvist, Johan Malm, Mathias Färnegårdh, Gary J. Grover, William Nelson, Marlena Grynfarb |
Rok vydání: |
2006 |
Předmět: |
|
Zdroj: |
Journal of Medicinal Chemistry. 49:6635-6637 |
ISSN: |
1520-4804 0022-2623 |
Popis: |
A new high-affinity thyroid hormone antagonist 6 with druglike properties was designed and synthesized. The compound behaved as an antagonist in a cell transactivation assay, and in a first in vivo experiment in rats. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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