Treatment of postherpetic neuralgia using DREZotomy guided by spinal cord stimulation
| Autor: | Jun Zhong, Jin Zhu, Ming-Xing Liu, Ning-Ning Dou, Lei Xia |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Microsurgery Visual analogue scale Neuralgia Postherpetic Spinal cord stimulation Herpes Zoster Symptom relief Monitoring Intraoperative medicine Humans Vas score Aged Pain Measurement Spinal Cord Stimulation Postherpetic neuralgia business.industry Dorsal root entry zone lesion Middle Aged medicine.disease Surgery Radiography Treatment Outcome Anesthesia Neuralgia Female Neurology (clinical) Complication business |
| Zdroj: | Stereotactic and functional neurosurgery. 93(3) |
| ISSN: | 1423-0372 |
| Popis: | Background: Postherpetic neuralgia (PHN) is the most common complication following an episode of acute herpes zoster. The curative effect of current treatments is limited. Objectives: The purpose of this paper is to report a new treatment for PHN with a combination of dorsal root entry zone lesion (DREZotomy) and spinal cord stimulation (SCS). Methods: Microsurgical DREZotomy assisted with SCS for target localization was performed in 6 patients with PHN. A visual analog scale (VAS) was used to evaluate the pain pre- and postoperatively. Results: Except for 1 patient, in whom the test SCS was unsatisfactory, all patients finally underwent DREZotomy. These 5 patients experienced apparent symptom relief postoperatively, and the VAS score decreased from a baseline of 8.4 ± 1.14 to 2.4 ± 1.14 (p = 0.0020) and did not change significantly during the follow-up of up to 24 months. Conclusions: Microsurgical DREZotomy assisted with SCS for target localization is an effective remedy for PHN. |
| Databáze: | OpenAIRE |
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