Rubella IgM epidemiology in the pre-rubella vaccination era in Uganda
| Autor: | Anette Kisakye, Richard Onyuthi Apecu, Edgar Mulogo, Fred Bagenda, Benard Toliva Opar |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male Pediatrics Rubella vaccine 0302 clinical medicine Medical microbiology Epidemiology Prevalence Rubella Vaccine Uganda 030212 general & internal medicine Child Aged 80 and over Transmission (medicine) Associated factors Middle Aged Vaccination Infectious Diseases Child Preschool Female medicine.drug Research Article Adult medicine.medical_specialty IgM Adolescent Rubella Syndrome Congenital Measles Rubella lcsh:Infectious and parasitic diseases 03 medical and health sciences Young Adult Age Distribution medicine Humans lcsh:RC109-216 Aged Retrospective Studies Congenital rubella syndrome business.industry Immunization Programs Infant medicine.disease 030104 developmental biology Immunoglobulin M Suspected measles cases business Rubella virus |
| Zdroj: | BMC Infectious Diseases BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-7 (2020) |
| ISSN: | 1471-2334 |
| Popis: | Background Control of Rubella and Congenital Rubella Syndrome using vaccination has shown great success in the America’s. Uganda is due to introduce the Rubella vaccine however the magnitude of transmission is not well documented. Therefore this study was done to determine IgM sero-prevalance for Rubella in order to help monitor vaccine effectiveness post introduction of the vaccine in routine vaccination programme. Methods A retrospective review of suspected measles cases data for the reporting period January 2007 to December 2016 in Uganda was Done. rubella IgM testing was done on 15,296 of the cases and the data was analyzed using STATA version 13. Results In total 15,296 cases were tested and 4255 (27.8%) tested positive and among females aged 15-49 years 88 out of 322 (27%) tested positive. The age distribution range was 0–80 years, rubella IgM positivity was reported in all the 15 regions of Uganda and throughout the ten year period in every month. Age group 5–15 years had OR 2.5 p-value Conclusion Rubella is endemic in Uganda and although rubella IgM positivity is highest in the age 5-15 years even the younger, older and women of reprodutive age are affected. This means the risk of Congenital Rubella Syndrome is high hence the need to introduce the rubella vaccine for infants and pregnant mothers and continued surveillance to enhance its control. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink