Soy Protein-Based Infant Formulas with Supplemental Fructooligosaccharides: Gastrointestinal Tolerance and Hydration Status in Newborn Infants
| Autor: | Sonja Acosta, Geraldine E. Baggs, John Lasekan, Amy Mackey |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
Lutein fructooligosaccharides Oligosaccharides lcsh:TX341-641 Article Feces chemistry.chemical_compound Lycopene Double-Blind Method beta-Carotene term infants Humans Medicine Food science Soy protein Carotenoid chemistry.chemical_classification Nutrition and Dietetics Urine specific gravity business.industry Body Weight Infant Newborn carotenoids Infant Carbohydrate beta Carotene Infant Formula Gastrointestinal Tract Infant formula chemistry gastrointestinal tolerance Dietary Supplements Soybean Proteins Female business lcsh:Nutrition. Foods and food supply hydration Food Science soy infant formulas |
| Zdroj: | Nutrients Volume 7 Issue 4 Pages 3022-3037 Nutrients, Vol 7, Iss 4, Pp 3022-3037 (2015) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu7043022 |
| Popis: | Unlike milk-based infant formulas, soy-based infant formulas containing supplemental fructooligosaccharides (FOS) have not been clinically evaluated. A randomized, double-blind, 28 day parallel feeding trial compared gastrointestinal (GI) tolerance and hydration in healthy term newborn infants fed either a commercialized soy formula (with history of safe use) containing sucrose as 20% of total carbohydrate, no supplemental short-chain FOS (scFOS) and no mixed carotenoids (lutein, lycopene, beta-carotene) as a control (CF, n = 62 infants) or one of two experimental soy-based formulas, EF1 (n = 64) and EF2 (n = 62) containing scFOS (2.5 g/L) and mixed carotenoids. EF1 differed from EF2 by containing sucrose. Results indicated no significant study group differences (p > 0.05) in study completion rates (CF = 81, EF1 = 86, & EF2 = 87%), growth, mean rank stool consistency, stool frequency, formula intake, spit-up/vomit, and safety measures (urine specific gravity, USG hydration status and adverse events). Mean USGs for study groups were normal (< 1.03). The EF1 > CF group in percent yellow stools (p < 0.01 at age 14 days). In conclusion, the study suggested that term infants fed soy-based formulas supplemented with scFOS and mixed carotenoids, with or without sucrose in the 1st 35 days of infancy demonstrated good tolerance and hydration comparable to the control soy-based formula with history of safe use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|