Vascular risk in women with a history of severe preeclampsia
| Autor: | Nese Yucel, Ertan Adali, Temel Tan, Cihan Karadag, Gokhan Goynumer, Erdem Baskent |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
HELLP Syndrome medicine.medical_specialty Brachial Artery Disease Vascular risk Carotid Intima-Media Thickness Severity of Illness Index Insulin resistance Pre-Eclampsia Pregnancy Internal medicine medicine.artery medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Brachial artery Inverse correlation Gynecology medicine.diagnostic_test business.industry medicine.disease Severe preeclampsia Vasodilation Cross-Sectional Studies Case-Control Studies Linear Models cardiovascular system Cardiology Female Ultrasonography business Lipid profile |
| Zdroj: | Journal of Clinical Ultrasound. 41:145-150 |
| ISSN: | 0091-2751 |
| DOI: | 10.1002/jcu.21962 |
| Popis: | Background. To assess markers of vascular dysfunction and risk in postpartum women with a history of severe preeclampsia. Methods. Carotid intima-media thickness (CIMT) and brachial artery flow-mediated dilatation (FMD) measured by ultrasonography, and lipid profile and insulin resistance evaluated by biochemical assays were compared between 34 women with a history of severe preeclampsia and 42 women with a prior normal pregnancy at least 1224 months postpartum. Results. CIMT was higher and FMD lower in the preeclamptic than in the control group. We found a significant inverse correlation between CIMT and FMD in the preeclamptic group, but no difference in lipid profiles and insulin resistance between the groups. Conclusions. Women with a history of severe preeclampsia exhibit early structural and functional preatherosclerotic vascular impairment, which might explain their higher risk of future cardiovascular disease. (c) Wiley Periodicals, Inc. J Clin Ultrasound 41:145-150, 2013; Published online in Wiley Online Library (wileyonlinelibrary.com). DOI: 10.1002/jcu.21962 |
| Databáze: | OpenAIRE |
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