Are inflammatory parameters predictors of amputation in acute arterial occlusions?
| Autor: | Kazım Serhan Özcan, Çağrı Düzyol, Uğur C Koçoğulları, Hüseyin Şaşkin, Ozgur Baris |
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| Rok vydání: | 2016 |
| Předmět: |
Erythrocyte Indices
Male Time Factors Neutrophils medicine.medical_treatment Embolectomy Femoral artery 030204 cardiovascular system & hematology 0302 clinical medicine Risk Factors Odds Ratio 030212 general & internal medicine Aged 80 and over medicine.diagnostic_test biology Complete blood count General Medicine Middle Aged Limb Salvage C-Reactive Protein Treatment Outcome Area Under Curve Acute Disease Cardiology Female Inflammation Mediators Cardiology and Cardiovascular Medicine Mean Platelet Volume Adult Reoperation medicine.medical_specialty Arterial Occlusive Diseases Amputation Surgical 03 medical and health sciences Predictive Value of Tests Internal medicine medicine.artery medicine Humans Radiology Nuclear Medicine and imaging Lymphocyte Count Mean platelet volume Aged Retrospective Studies Platelet Count business.industry C-reactive protein Red blood cell distribution width medicine.disease Surgery Logistic Models ROC Curve Amputation Embolism Multivariate Analysis biology.protein business Biomarkers |
| Zdroj: | Vascular. 25:170-177 |
| ISSN: | 1708-539X 1708-5381 |
| Popis: | BackgroundThe aim of the present study was to investigate the role of inflammatory markers to predict amputation following embolectomy in acute arterial occlusion.MethodsA total of 123 patients operated for arterial thromboembolectomy due to acute embolism were included in the study. The patients without an extremity amputation following thromboembolectomy were classified as Group 1 ( n = 91) and the rest were classified as Group 2 ( n = 32). These groups were compared in terms of clinical and demographic characteristics, C-reactive protein, complete blood count parameters, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and red cell distribution width.ResultsThe average age was 68.0 ± 11.7 years. The most common thromboembolism localization was femoral artery. When preoperative mean C-reactive protein ( p = 0.0001), mean platelet volume ( p = 0.0001), platelet-lymphocyte ratio ( p = 0.0001), neutrophil-lymphocyte ratio ( p = 0.0001) and red cell distribution width ( p = 0.0001) were compared, a statistically significant difference was observed between groups. In univariate and multivariate regression analysis, higher levels of preoperative C-reactive protein ( p = 0.009) and mean platelet volume ( p = 0.04) were detected as independent risk factors of early extremity amputation.ConclusionWe observed that preoperative mean platelet volume and C-reactive protein were predictors of amputation after thromboembolectomy in acute arterial occlusion. |
| Databáze: | OpenAIRE |
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