Outcomes of sinonasal oncocytic papilloma by endoscopic approach in 69 patients
| Autor: | Xicai Sun, Changwen Zhai, Dehui Wang, Rui Xu, Huankang Zhang, Huan Wang, Quan Liu, Hongmeng Yu |
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| Rok vydání: | 2022 |
| Předmět: |
Male
Nasal cavity medicine.medical_specialty Maxillary sinus Nose Neoplasms Kaplan-Meier Estimate 03 medical and health sciences 0302 clinical medicine Ethmoid sinus Paranasal Sinuses medicine Humans 030223 otorhinolaryngology Sinus (anatomy) Neoplasm Staging Proportional Hazards Models Retrospective Studies Analysis of Variance Frontal sinus Univariate analysis business.industry Endoscopy General Medicine Middle Aged medicine.disease Surgery medicine.anatomical_structure Otorhinolaryngology Dysplasia 030220 oncology & carcinogenesis Papilloma Female Neoplasm Recurrence Local business Paranasal Sinus Neoplasms |
| Zdroj: | Auris Nasus Larynx. 49:77-83 |
| ISSN: | 0385-8146 |
| Popis: | Sinonasal oncocytic papilloma (SOP) is a rare subtype of sinonasal papilloma. There are currently few reports on its clinical features and outcomes after endoscopic surgical resection. This study aims to explore the clinical characteristics of SOP and potential factors predicting tumor recurrence through a single-center retrospective case series analysis.We conducted a retrospective analysis of 69 patients who underwent endoscopic surgery of SOP from June 2012 to April 2019. The data of patients' demographics, clinical features, follow-up period, and treatment outcomes were collected.The series includes 43 males and 26 females with an average age of 60.2 years. The tumor commonly involved the nasal cavity (n = 59; 89.4%), followed by maxillary sinus (n = 31; 44.9%), ethmoid sinus (n = 28; 40.6%), frontal sinus (n = 6; 8.7%) and sphenoid sinus (n = 6; 8.7%). The follow-up period ranged from 3 months to 96 months (mean, 34.6 months) and nine patients (13%) developed tumor recurrence during the follow-up period. Univariate analysis found that the recurrence of SOP was significantly related to tumor attachment site, Oikawa tumor stage, and histological dysplasia (p0.05). Multivariate COX regression analysis found that Oikawa staging system (p = 0.024) and presence of dysplasia (p = 0.04) were significantly related to tumor recurrence.SOP had low recurrence rate which was comparable to sinonasal inverted papilloma in the endoscopic era. Our findings also demonstrated that presence of dysplasia is an independent prognostic factor for recurrence free survival. |
| Databáze: | OpenAIRE |
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