Review of 'Digital image forensics: There is more to a picture than meets the eye' by Husrev Taha Sencar and Nasir Memon (Editors)
| Autor: | Corinne L Stephenson, Marilyn M. Bui |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Endometrial adenocarcinoma
Pathology medicine.medical_specialty Scanner High magnification business.industry Magnification Health Informatics Cervicovaginal cytology lcsh:Computer applications to medicine. Medical informatics Computer Science Applications Pathology and Forensic Medicine Digital image Cytopathology medicine Commentary lcsh:Pathology lcsh:R858-859.7 Medical physics business Image resolution lcsh:RB1-214 |
| Zdroj: | Journal of Pathology Informatics, Vol 4, Iss 1, Pp 18-18 (2013) Journal of Pathology Informatics |
| ISSN: | 2153-3539 |
| Popis: | The successful integration of digital cytopathology into daily practice presents unique challenges. Whole slide imaging (WSI) of cytologic specimens must provide high resolution images on small cellular areas. Fine focus at high magnification is important for evaluation of three dimensional objects such as hyperchromatic crowded groups in cervicovaginal cytology.[1] The introduction of z-axis focusing in which multiple planes in the z-axis are scanned and incorporated in the final image called a “z-stack” allows for the fine focus functionality required in the subspecialized field of cytopathology.[2] The evaluation of diagnostic digital cytopathology in liquid-based cervicovaginal smears has been limited. A recent study by Wright et al., at Weill Cornell Medical College of Cornell University in Houston, Texas attempted to discover the advantages and limitations of WSI in this area.[3] Seven participants (3 pathologists and 4 cytotechnologists) examined 11 cervicovaginal papanicolaou smears (Thin-Prep and SurePath) which were scanned at ×20, ×40 and ×40 z-stack digital magnifications using the BioImagene iScan Coreo Au 3.0 scanner. The digital images were viewed on a computer equipped with an Intel Pentium 3.44-GHz processor, 1 GB RAM, 64 MB VRAM and a display monitor with 1600 × 1024 pixel resolution. The diagnosis and time to reach a diagnosis were recorded. The results were compared with manually reading the same glass slides. The results showed that accuracy of interpretation and the time to reach a diagnosis was superior with glass slides as compared with all of the digital magnifications. When the different digital magnifications were compared, ×40 and ×40 with z-stack had better accuracy and a shorter time to diagnosis than the ×20 magnification. The authors noted that the ×40 z stack imaging performed better in the diagnosis of endometrial adenocarcinoma and commented on the usefulness of WSI cytology in archiving for storage and future comparison, especially if the specimen was used entirely for ancillary testing. However, due to the diagnostic and technologic difficulties presented by WSI, the authors concluded that WSI in cervicovaginal cytology is not ready for daily screening and diagnosis. This finding is somewhat discouraging considering liquid-based specimens have a smaller cellular area to scan, screen and diagnose, which was anticipated as a promising area of early adoption of digitalization. |
| Databáze: | OpenAIRE |
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