Development of a Mesoscale Pulsed Discharge Helium Ionization Detector for Portable Gas Chromatography
| Autor: | Michael A. Mangan, Ronald P. Manginell, Elizabeth Schares Sparks, Komandoor E. Achyuthan, Adam S. Pimentel, Matthew W. Moorman, Curtis D. Mowry, Amy Allen |
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| Rok vydání: | 2015 |
| Předmět: |
Chromatography
Gas Miniaturization Instrumentation Helium ionization detector Detector Analytical chemistry chemistry.chemical_element Stainless Steel Helium Analytical Chemistry chemistry Pulsed discharge ionization detector Humans Gas chromatography Discharge ionization detector Caproates Electrodes |
| Zdroj: | Analytical Sciences. 31:1183-1188 |
| ISSN: | 1348-2246 0910-6340 |
| Popis: | Miniaturization of gas chromatography (GC) instrumentation enables field detection of volatile organic compounds (VOCs) for chembio-applications such as clandestine human transport and disease diagnostics. We fabricated a mesoscale pulsed discharge helium ionization detector (micro-PDHID) for integrating with our previously described mini-GC hardware. Stainless steel electrodes fabricated by photochemical etching and electroforming facilitated rapid prototyping and enabled nesting of inter-electrode insulators for self-alignment of the detector core during assembly. The prototype was ∼10 cm(3) relative to >400 cm(3) of a commercial PDHID, but with a comparable time to sweep a VOC peak from the detector cell (170 ms and 127 ms, respectively). Electron trajectory modeling, gas flow rate, voltage bias, and GC outlet location were optimized for improving sensitivity. Despite 40-fold miniaturization, the micro-PDHID detected 18 ng of the human emanation, 3-methyl-2-hexenoic acid with |
| Databáze: | OpenAIRE |
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