Eosinophilic Granulomatosis with Polyangiitis Relapse after COVID-19 Vaccination: A Case Report

Autor:	Giulia Costanzo, Andrea Giovanni Ledda, Alessandra Ghisu, Matteo Vacca, Davide Firinu, Stefano Del Giacco
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Pharmacology relapse mRNA BNT162b2 vaccine Infectious Diseases vaccine Drug Discovery Immunology COVID-19 Medicine Case Report Pharmacology (medical) EGPA
Zdroj:	Vaccines, Vol 10, Iss 13, p 13 (2022) Vaccines
Popis:	Background: We here describe the case of a 71-year-old Caucasian woman previously diagnosed with Eosinophilic Granulomatosis with Polyangiitis (EGPA) that had been treated with Mepolizumab, an anti-IL5 monoclonal antibody, since 2019 with a good clinical response. Methods: She had a mild COVID-19 in December 2020 and she tested negative for SARS-CoV-2 infection in only late January 2021. In April 2021 she received the first dose of mRNA BNT162b2 vaccine. Ten days later she developed myalgia, dyspnea and numbness of the limbs due to a relapse of EGPA that occurred during Mepolizumab treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ad9e140fc2585d7170caf02caffee1 https://www.mdpi.com/2076-393X/10/1/13 Zobrazit plný text záznamu