Enhanced detection of respiratory pathogens with nanotrap particles
| Autor: | Katherine Fite, Kylene Kehn-Hall, Benjamin Lepene, Nazly Shafagati, Alan Baer, Alexis Patanarut, Chelsea Pinkham, Benjamin Foote, Soyeon An |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Saliva biology Respiratory tract infections 030106 microbiology Immunology Orthomyxoviridae medicine.disease_cause biology.organism_classification medicine.disease Microbiology Virology Virus Respiratory pathogens 03 medical and health sciences 030104 developmental biology Infectious Diseases medicine Coinfection Parasitology Respiratory system Coronavirus |
| Zdroj: | Virulence |
| ISSN: | 2150-5608 2150-5594 |
| DOI: | 10.1080/21505594.2016.1185585 |
| Popis: | The Influenza virus is a leading cause of respiratory disease in the United States each year. While the virus normally causes mild to moderate disease, hospitalization and death can occur in many cases. There are several methodologies that are used for detection; however problems such as decreased sensitivity and high rates of false-negative results may arise. There is a crucial need for an effective sample preparation technology that concentrates viruses at low abundance while excluding resident analytes that may interfere with detection. Nanotrap particles are hydrogel particles that are coupled to chemical dye affinity baits that bind a broad range of proteins and virions. Within minutes ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
| Nepřihlášeným uživatelům se plný text nezobrazuje | K zobrazení výsledku je třeba se přihlásit. |