| Autor: |
Cheng Peng, Li-jun Yang, Chuan Zhang, Yu Jiang, Liu-wen-xin Shang, Jia-bei He, Zhen-wei Zhou, Xia Tao, Lu Tie, Alex F. Chen, He-hui Xie |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Acta pharmacologica Sinica. 44(1) |
| ISSN: |
1745-7254 |
| Popis: |
It is of great clinical significance to develop potential novel strategies to prevent diabetic cardiovascular complications. Endothelial progenitor cell (EPC) dysfunction is a key contributor to diabetic vascular complications. In the present study we evaluated whether low-dose nifedipine could rescue impaired EPC-mediated angiogenesis and prevent cardiovascular complications in diabetic mice. Diabetes was induced in mice by five consecutive injections of streptozotocin (STZ, 60 mg·kg |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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