A magnetic induction heating system with multi-cascaded coils and adjustable magnetic circuit for hyperthermia

Autor: Hsuan Yi Chao, Chi-Fang Huang, Xi-Zhang Lin, Hsun Hao Chang
Rok vydání: 2014
Předmět:
Zdroj: Electromagnetic Biology and Medicine. 35:59-64
ISSN: 1536-8386
1536-8378
DOI: 10.3109/15368378.2014.977390
Popis: Based on the characteristics of cancer cells that cannot survive in an environment with temperature over 42 °C, a magnetic induction heating system for cancer treatment is developed in this work. First, the methods and analyses for designing the multi-cascaded coils magnetic induction hyperthermia system are proposed, such as internal impedance measurement of power generator, impedance matching of coils, and analysis of the system. Besides, characteristics of the system are simulated by a full-wave package for engineering optimization. Furthermore, by considering the safety factor of patients, a two-sectional needle is designed for hyperthermia. Finally, this system is employed to test the liver of swine in ex-vivo experiments, and through Hematoxylin and Eosin (H&E) stain and NADPH oxidase activity assay, the feasibility of this system is verified.
Databáze: OpenAIRE