Biaryl sulfonamides as cisoid azosteres for photopharmacology
| Autor: | Martin D. Witte, Sebastian Thallmair, Ben L. Feringa, Piermichele Kobauri, Siewert J. Marrink, Wiktor Szymanski, Frank J. Dekker, Fangyuan Cao |
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| Přispěvatelé: | Synthetic Organic Chemistry, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Chemical and Pharmaceutical Biology, Molecular Dynamics, Chemical Biology 2, Medicinal Chemistry and Bioanalysis (MCB), Biopharmaceuticals, Discovery, Design and Delivery (BDDD) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Scope (project management)
010405 organic chemistry Computer science Metals and Alloys Rational design General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences 3. Good health Surfaces Coatings and Films Electronic Optical and Magnetic Materials Materials Chemistry Ceramics and Composites |
| Zdroj: | Chemical Communications Chemical Communications, 57(34), 4126-4129. ROYAL SOC CHEMISTRY |
| ISSN: | 1359-7345 |
| Popis: | Biaryl sulfonamides are excellent candidates for the azologization approach that yields photoswitchable drugs more active in their metastable cis state, compared to the stable trans state. Here we present the scope and limitations of this strategy for rational design in photopharmacology. |
| Databáze: | OpenAIRE |
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