Cerebral palsy in twins and higher multiple births: a Europe‐Australia population‐based study
| Autor: | Sellier, Ellodie, Goldsmith, Shona, McIntyre, Sarah, Perra, Oliver, Rackauskaite, Gija, Badawi, Nadia, Fares, Asma, Smithers-Sheedy, Hayley, Collaborators: Ego, A, Tronc, C, Arnaud, C, Delobel, M, Mc Manus, V, Lyons, A, Perra, O, McConnel, K, Himmelmann, K, Pahlman, M, Hensey, O, Dowding, V, Kurinczuk, J, Rackauskaite, G, Laursen, B, Torrioli, MG, Marcelli, M, Andersen, GL, Julsen Hollung, S, Bottos, M, Gaffney, G, de la Cruz, J, Pallas, C, Neubauer, D, Radsel, A, Virella, D, Folha, T, Greitane, A, Hollody, Csabi, G, Đaković, Ivana, Sigurðardóttir, S, Einarsson, I, Haberlandt, E, Ortibus, E, Franki, I, Mejaški- Bošnjak, Vlatka, Kuenzle, C, Tscherter, A, Attard, S, Papavasilou, A, Horridge, K, Platt, MJ, Krägeloh-Mann, I, Horber, V, Auld, M, Badawi, N, Blair, E, Diviney, L, Gibson, C, Gibson, N, Goldsmith, S, Gration, D, Hernandez, J, Langdon, K, Love, S, Maloney, E, Martin, T, McIntyre, S, Kay, F, O'Grady, G, Reddihough, D, Reid, S, Scott, H, Smithers-Sheedy, H, Watson, L |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Risk 030506 rehabilitation medicine.medical_specialty Population Clinical Neurology Gestational Age Multiple Birth Offspring Cerebral palsy 03 medical and health sciences Epilepsy 0302 clinical medicine Developmental Neuroscience Pregnancy medicine Prevalence Birth Weight Humans Registries Pediatrics Perinatology and Child Health cerebral palsy twins education Denominator data education.field_of_study Obstetrics business.industry Cerebral Palsy Australia Gestational age Gross Motor Function Classification System medicine.disease Confidence interval Europe Quadruplets Cross-Sectional Studies Child Preschool Pediatrics Perinatology and Child Health Premature Birth Female Neurology (clinical) 0305 other medical science business 030217 neurology & neurosurgery |
| Zdroj: | The Surveillance Of Cerebral Palsy Europe Group And The Australian Cerebral Palsy Register Group 2021, ' Cerebral palsy in twins and higher multiple births: a Europe-Australia population-based study ', Developmental Medicine and Child Neurology, vol. 63, no. 6, pp. 712-720 . https://doi.org/10.1111/dmcn.14827 Surveillance Of Cerebral Palsy Europe Group And The Australian Cerebral Palsy Register Group 2021, ' Cerebral palsy in twins and higher multiple births : a Europe-Australia population-based study ', Developmental Medicine and Child Neurology, vol. 63, no. 6, pp. 712-720 . https://doi.org/10.1111/dmcn.14827 |
| DOI: | 10.1111/dmcn.14827 |
| Popis: | Aim:To describe the birth prevalence, temporal trends, and clinical outcomes of twins, triplets, or quadruplets with cerebral palsy (CP).Method:This was a cross-sectional study using data for twins, triplets, and quadruplets with prenatally or perinatally acquired CP and pooled from the Surveillance of Cerebral Palsy in Europe network (born 1992–2009) and Australian Cerebral Palsy Register (born 1993–2009). Children were at least 4 years old at time of registration. Children born in regions with population ascertainment and available denominator data were included in prevalence calculations (n=1033 twins, 81 triplets, and 11 quadruplets). Clinical data from children registered in all participating registers were described, including 2163 twins (56% male), 187 triplets (59% male), and 20 quadruplets (45% male).Results:The birth prevalence of CP was higher with increasing plurality (twins 6.5 per 1000 live births [95% confidence interval {CI} 6.1–6.9], triplets 17.1 [95% CI 13.6–21.2], quadruplets 50.7 [95% CI 25.6–88.9]); however, prevalence by gestational age was similar across all pluralities. Between 1992–1994 and 2007–2009, prevalence of CP among twins declined (p=0.001) but prevalence of CP among triplets did not change significantly over time (p=0.55). The distributions of Gross Motor Function Classification System, epilepsy, and impairments of intellect, vision, and hearing were similar regardless of plurality.Interpretation:The data combined from two CP register networks indicated that triplets and quadruplets had increased risk of CP compared to twins. The higher prevalence of CP in triplets and quadruplets is due to their higher risk of preterm birth. Prevalence of CP among twins significantly declined in Europe and Australia. Clinical outcomes were similar for all multiple births. |
| Databáze: | OpenAIRE |
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