Microscopic colitis in Denmark and Sweden: incidence, putative risk factors, histological assessment and endoscopic activity
| Autor: | Klas Sjöberg, Lina Vigren, Sanna Davidson, Esther Lo¨rinc, Anne Marie Kanstrup Fiehn, Lars Kristian Munck, Peter Johan Heiberg Engel |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Biopsy Denmark Newly diagnosed Drug Prescriptions Gastroenterology Young Adult 03 medical and health sciences Age Distribution 0302 clinical medicine Microscopic colitis Risk Factors Internal medicine Epidemiology medicine Humans Sex Distribution Aged Aged 80 and over Sweden medicine.diagnostic_test business.industry Incidence Incidence (epidemiology) Anti-Inflammatory Agents Non-Steroidal Endoscopy Proton Pump Inhibitors Middle Aged medicine.disease Colitis Microscopic 030220 oncology & carcinogenesis Female 030211 gastroenterology & hepatology business Selective Serotonin Reuptake Inhibitors |
| Zdroj: | Scandinavian Journal of Gastroenterology. 53:818-824 |
| ISSN: | 1502-7708 0036-5521 |
| Popis: | The significantly higher incidence rates of microscopic colitis (MC) in Denmark compared to Sweden remains unexplained.Consecutive patients with newly diagnosed MC in the neighbouring regions of Skåne in 2011-2015 and Zealand in 2010-2016 were prospectively identified. Data on large bowel endoscopies and biopsies rates were retrieved. Information on putative factors were obtained from registers and literature. Interobserver agreement between pathologists from both regions on 40 blinded hematoxylin and eosin (HE)-stained colon biopsies (collagenous colitis (CC), lymphocytic colitis (LC), non-specific inflammation and normal) was evaluated using kappa statistics.The mean annual incidence per 10The incidence of MC and number of cases per colonic biopsy was higher in Zealand and could not be readily explained by endoscopy or biopsy rates, differences in histological assessment or putative risk factors. |
| Databáze: | OpenAIRE |
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