Paclitaxel-eluting stents reduce neointimal hyperplasia compared to bare metal stents in saphenous vein grafts: intravascular ultrasonography analysis of the SOS (Stenting of Saphenous Vein Grafts) trial
| Autor: | Monica daSilva, Bilal Saeed, Abdul Rahman R Abdel-Karim, James D. Rossen, Vassilios V. Voudris, Omar M. Jeroudi, Rajesh Sachdeva, Bavana V. Rangan, Emmanouil S. Brilakis, Christopher Lichtenwalter, Panayotis Fasseas, Tayo Addo, Panagiotis Karyofillis, Owen Obel, Biswajit Kar, Joe K. Bissett, Deepa Raghunathan, Peter B. Berger, Donald Haagen, James A. de Lemos, Subhash Banerjee, Michele Roesle, Tesfaldet T. Michael |
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| Rok vydání: | 2011 |
| Předmět: |
Neointima
Male medicine.medical_specialty Paclitaxel medicine.medical_treatment Lumen (anatomy) Vein graft chemistry.chemical_compound medicine Humans Saphenous Vein cardiovascular diseases Intravascular ultrasonography Ultrasonography Interventional Aged Neointimal hyperplasia Hyperplasia business.industry Stent Drug-Eluting Stents Middle Aged equipment and supplies medicine.disease Antineoplastic Agents Phytogenic surgical procedures operative chemistry Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. 7(8) |
| ISSN: | 1969-6213 |
| Popis: | AIMS To compare the intravascular ultrasonography (IVUS) findings between saphenous vein grafts (SVG) treated with paclitaxel-eluting stents (PES) vs. bare metal stents (BMS) in the Stenting Of Saphenous Vein Grafts (SOS) trial. METHODS AND RESULTS Of the 80 SOS trial patients, 38 had both baseline and follow-up IVUS examination and were included in this substudy: 17 patients received 28 BMS in 26 lesions and 21 patients received 30 PES in 28 lesions. Quantitative IVUS analysis was performed to determine the volume of in-stent neointimal hyperplasia (NIH) - defined as the difference between stent volume and lumen volume in the stented segments. Baseline characteristics were similar between patients who did and did not undergo baseline and follow-up IVUS. Patients receiving BMS and PES had similar stent and lumen volumes immediately after stenting. At 12-month follow-up, compared to BMS, PES-treated lesions had significantly less NIH volume (3.4 vs. 21.9 mm³, p |
| Databáze: | OpenAIRE |
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