L-Thyroxine induces thermotolerance in yeast
| Autor: | Constantinos Pantos, Iordanis Mourouzis, Basil Delitheos, Konstantinos Papamichael, Ekaterini Tiligada |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Thermotolerance Saccharomyces cerevisiae Proteins Cell Survival Short Communication 030106 microbiology Saccharomyces cerevisiae Biochemistry 03 medical and health sciences Cellular stress response Heat shock protein HSP90 Heat-Shock Proteins Heat shock biology Chemistry Cell Biology biology.organism_classification Hsp90 Yeast Cell biology Proton-Translocating ATPases Thyroxine 030104 developmental biology biology.protein Hormone |
| Zdroj: | Cell stresschaperones. 24(2) |
| ISSN: | 1466-1268 |
| Popis: | The cellular stress response (CSR) is a universal inducible reaction modulated, among others, by heat, drugs, and hormones. We aimed to investigate the role of l-thyroxine (T4) on the heat shock (HS) response in Saccharomyces cerevisiae. The CSR was evaluated by determining growth and viability of post-logarithmic phase grown yeast cultures after HS at 53 °C for 30 min. We found that long-term T4 exposure can induce a dose-dependent and Hsp90 and H(+) trafficking-related thermotolerance in yeast. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink