Erosive pustular dermatosis of the scalp: a multicentre study
| Autor: | Vincenzo Piccolo, Sergio Vano-Galvan, Ralph M. Trüeb, Aurora Alessandrini, Francesca Bruni, Andy Goren, Michela Starace, Francisco Camacho, Matilde Iorizzo, Lidia Rudnicka, Anna Lyakhovitsky, Y Gallyamova, Bianca Maria Piraccini, I. Umbert, Giuseppe Argenziano |
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| Přispěvatelé: | Starace M, Iorizzo M, Trüeb RM, Piccolo V, Argenziano G, Camacho FM, Gallyamova Y, Rudnicka L, Umbert I, Lyakhovitsky A, Vañó-Galván S, Goren A, Alessandrini A, Bruni F, Piraccini BM., Starace, M., Iorizzo, M., Trueb, R. M., Piccolo, V., Argenziano, G., Camacho, F. M., Gallyamova, Y., Rudnicka, L., Umbert, I., Lyakhovitsky, A., Vano-Galvan, S., Goren, A., Alessandrini, A., Bruni, F., Piraccini, B. M. |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Erosive pustular dermatosis of the scalp squamous cell carcinoma steroids tracrolimus trichoscopy medicine.medical_treatment Hyperkeratosis Cryotherapy Dermatology Scarring alopecia Tacrolimus 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine Humans Retrospective Studies Scalp business.industry Alopecia Middle Aged medicine.disease Trichoscopy Serous fluid Infectious Diseases medicine.anatomical_structure Scalp Dermatoses 030220 oncology & carcinogenesis Histopathology Female business |
| Popis: | Background Erosive pustular dermatosis of the scalp (EPDS) is characterized by crusted erosions or superficial ulcerations that lead to scarring alopecia. Objectives and methods We performed a multicentre retrospective clinical study including 56 patients (29 females and 27 males, mean age 62.7) with a confirmed EPDS in order to describe epidemiology, clinical findings and therapeutic choices of this disease. Results Mechanical/chemical trauma was reported in 28.6%, a previous infection in 10.7%, a previous cryotherapy in 5.4% androgenetic alopecia in 48.2% and severe actinic damage in 25%. Trichoscopy showed absence of follicular ostia, tufted and broken hair, crusts, serous exudate, dilated vessels, pustules and hyperkeratosis. Histopathology revealed three different features, depending on the disease duration. The most prescribed therapy was topical steroids (62.5%), followed by the combination of topical steroids and topical tacrolimus (8.9%), systemic steroids (7.1%) and topical tacrolimus (5.4%). A reduction of inflammatory signs was observed in 28 patients (50%) treated with topical steroids and in all three patients treated with topical tacrolimus. Conclusion The relatively high number of patients collected allowed us to identify a better diagnostic approach, using trichoscopy and a more effective therapeutic strategy, with high-potency steroids or tacrolimus, which should be considered as first-line treatment. |
| Databáze: | OpenAIRE |
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