A new polyphenol, 1, 3-di-O-caffeoyl-5-O-(1-methoxyl-2-O-caffeoyl-4-maloyl)-quinic acid, isolated from cultured cells of Saussurea involucrata

Autor:	Xiao-Wei Zou, Dan Liu, Hong-bin Xiao, Zhilong Xiu, Ya-Ping Liu
Rok vydání:	2014
Předmět:	Saussurea ABTS Vitamin C DPPH Stereochemistry Polyphenols General Medicine Quinic acid In vitro Antioxidants chemistry.chemical_compound Complementary and alternative medicine chemistry Polyphenol Drug Discovery Spectral analysis Cells Cultured Saussurea involucrata
Zdroj:	Chinese journal of natural medicines. 13(4)
ISSN:	1875-5364
Popis:	The present study was designed to isolate the polyphenol constituents of cultured cells of Saussurea involucrata. The polyphenol type constituents were isolated using chromatography methods, and then characterized by spectral analysis. 1,1-Diphenyl-2-picrylhydrazyl radical 2,2-Diphenyl-1-(2,4,6-trinitrophenyl)-hydrazyl (DPPH) and 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) free radical scavenging were assayed using Vitamin C as the positive control. One new polyphenol 18, 1, 3-di-O-caffeoyl-5-O-(1-methoxyl-2-O-caffeoyl-4-maloyl)-quinic acid, together with 17 known compounds, was isolated and characterized. In conclusion, Compound 18 was a new caffeoyl maloyl quinic acid type polyphenol and showed desired vitro anti-oxidant activity. Compounds 1-5, 9, 10, 14, 15, and 17 were isolated from cultured cells of Saussurea involucrata for the first time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0685bb0050956f0f85111a1a1e49ec6 https://pubmed.ncbi.nlm.nih.gov/25908627 Zobrazit plný text záznamu Full Text from ScienceDirect