Putative Therapeutic Impact of Inflammasome Inhibitors against COVID-19-Induced ARDS

Autor: Seyed Fazel, Nabavi, Adeleh, Sahebnasagh, Ahad, Shahbazi, Seyed Mohammad, Nabavi, Mojde, Rahmani, Saeid, Azimi, Malihe Khayat, Kashani, Solomon, Habtemariam, Mohadese, Badiee, Javad, Hashemi, Fatemeh, Saghafi, Kiumarth, Amini, Mina, Azimi, Aysa, Rezabakhsh
Rok vydání: 2023
Předmět:
Zdroj: Current Medicinal Chemistry. 30:1406-1419
ISSN: 0929-8673
DOI: 10.2174/0929867329666220906111550
Popis: Abstract: Given the importance of COVID-19-induced ARDS, recently, researchers have strived to determine underlying mechanisms involved in the inflammatory responses. In this regard, inflammasomes possess a distinct priority for cytokine storm occurrence and, subsequently, ARDS progression in ill patients with SARS-CoV-2 infection. In this minireview, the characteristics of known inflammasome inhibitors and designed research in this field were concretely deciphered.
Databáze: OpenAIRE