A rare cardiac neoplasm: case report of cardiac epithelioid angiosarcoma
| Autor: | Margaret A. Knowling, Michael F. Allard, Dennis R. Grant, Lise Matzke, Andrew Ignaszewski, Jonathon Leipsic, James B. Cupples |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
CD31 medicine.medical_specialty Pathology Cardiac Neoplasm Hemangiosarcoma Vimentin Pathology and Forensic Medicine Heart Neoplasms Fatal Outcome medicine.artery Atrial Fibrillation Biomarkers Tumor medicine Humans Neoplasm Aorta Abdominal Heart Atria Aorta biology business.industry Epithelioid Cells Atrial fibrillation General Medicine Middle Aged medicine.disease Combined Modality Therapy stomatognathic diseases cardiovascular system biology.protein Immunohistochemistry Radiology Cardiology and Cardiovascular Medicine business Epithelioid cell Echocardiography Transesophageal |
| Zdroj: | Cardiovascular Pathology. 20:e197-e201 |
| ISSN: | 1054-8807 |
| Popis: | Primary cardiac angiosarcoma is a rare neoplasm and the epithelioid variant is exceedingly rare. We report a case of an epithelioid angiosarcoma that involved the right atrium and aorta of a 47-year-old male. The patient presented with atrial fibrillation and presyncopal spells. Following clinical evaluation, including computed tomography scan and trans-esophageal echocardiography, the neoplasm was surgically removed. It was a poorly differentiated malignant neoplasm composed of medium-sized epithelioid cells with a moderate amount of amphophilic cytoplasm. Immunohistochemical staining, including positive staining for CK22, AE1/AE3, melan-A, vimentin, and CD31, indicated the neoplasm was best categorized as an epithelioid angiosarcoma. |
| Databáze: | OpenAIRE |
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