A Novel, Efficient, Unit Circle-Based, Method for Positioning and Operating Cryo-Surgical Probes in Convex Target Areas
Autor: | Z. Magalov, Degani David, Shitzer Avraham |
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Rok vydání: | 2020 |
Předmět: |
0106 biological sciences
0301 basic medicine Physics Temperature Biomedical Engineering Regular polygon Tangent Geometry Cryosurgery 01 natural sciences Radius of curvature (optics) 03 medical and health sciences 030104 developmental biology Unit circle Needles Physiology (medical) Margin of safety Single probe 010606 plant biology & botany |
Zdroj: | Journal of Biomechanical Engineering. 143 |
ISSN: | 1528-8951 0148-0731 |
DOI: | 10.1115/1.4048402 |
Popis: | A novel method for positioning and operating needle-like cryo-surgical probes in 2D convex target areas is presented. The method is based on the recorded dynamic performance of a single probe, termed “unit circle,” (UC) embedded in a semi-infinite, tissue-like medium. Up to 15 cryo-probes, inserted into the same depth, are operated uniformly for 2–5 min. A predetermined number of probes are rearranged inside the target area until a “tight configuration” is obtained. The probes are initially arranged inside the target area such that the “lethal temperature” circles produced by them are tangent to its contour and to both adjacent lethal temperature circles. Subsequently, all probes are repositioned inwardly, each at a specific distance that depends on the local radius of curvature of the target area. Resulting total “defect areas”—internal and external—for a number of demonstrated cases, amounted to between 2.5% and 7.6% of the target area. The lower values of the defect areas were obtained with increasing numbers of inserted probes coupled with shorter operating times. Possible freezing damages to regions beyond the target area were reduced by up to about 30% for these cases. Similar results were obtained for a case of combined convex-concave target area, treated with additional, externally inserted, heating probes. |
Databáze: | OpenAIRE |
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