Supplementary Figure 3 from Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment

Autor: Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
Rok vydání: 2023
Popis: IFNα enhances the response to TLR3 triggering by either poly-I:C or rintatolimod, but prostaglandin inhibition is selectively needed to optimize the pattern of inflammation induced by poly-I:C.
Databáze: OpenAIRE