Complexation and physicochemical analysis of hydrophobic molecules of methyl jasmonate with Hydroxypropyl-β–Cyclodextrin
| Autor: | Flávio Faria de Moraes, Lúcio Cardozo-Filho, Graciette Matiolli, Everton Fernando Zanoelo, Carlos Eduardo Barão, Osvaldo Valarini Junior |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
General Computer Science
DPPH General Mathematics complexation General Physics and Astronomy 02 engineering and technology 030226 pharmacology & pharmacy Absorbance 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Thermal stability lcsh:Science (General) chemistry.chemical_classification Methyl jasmonate Supercritical carbon dioxide Cyclodextrin organic molecule General Engineering General Chemistry Chemical Engineering 021001 nanoscience & nanotechnology Hydrophobe chemistry cyclodextrin physicochemical characterization lcsh:TA1-2040 General Earth and Planetary Sciences Absorption (chemistry) 0210 nano-technology lcsh:Engineering (General). Civil engineering (General) Nuclear chemistry lcsh:Q1-390 |
| Zdroj: | Acta Scientiarum: Technology, Vol 41, Iss 1, Pp e39611-e39611 (2019) Acta Scientiarum. Technology; Vol 41 (2019): Publicação Contínua; e39611 Acta Scientiarum. Technology; v. 41 (2019): Publicação Contínua; e39611 Acta scientiarum. Technology Universidade Estadual de Maringá (UEM) instacron:UEM |
| ISSN: | 1807-8664 1806-2563 |
| Popis: | In the present study, methyl jasmonate (MeJa) was included in 2-hydroxypropyl-β-cyclodextrin (HPβCD) by grinding (M 1 ), freeze drying (M 2 ), co-precipitation + freeze drying (M 3 ) and by applying supercritical carbon dioxide (M 4 ). FT-IR/ATR, FT-Raman, TGA, and DSC analyses of the complexation products confirmed that MeJa/HPβCD complexes were formed by the four different examined methods of inclusion. FT-IR/ATR supported the inclusion, mainly based on the reduction of intensity of absorption at the wavelength of maximum absorbance of free MeJa (1733 cm -1 ), which was 27.69 au before inclusion. From these results, M 3 (2.29 au) and M 4 (0.90 au) were the most efficient techniques for complexation. TGA, and DSC analyses pointed out that the complexes formed by the methods M 3 and M 4 had the least loss of mass below approximately 305°C (the temperature that free HPβCD starts to decompose thermally). Except for M 1 , the results of antioxidant activity (AA) based on the DPPH assay revealed that the AA of the inclusion compounds were higher than that of free MeJa (α = 0.05). The best methods in terms of AA and thermal stability of the formed inclusion compounds were M 3 and M 4 . |
| Databáze: | OpenAIRE |
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